名稱 | EGFR p.G719S Reference Standard 標準品 |
型號 | CBP10267 |
報價 | |
特點 | EGFR p.G719S Reference Standard |
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聯(lián)系人:蔣經(jīng)理
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地址:南京市棲霞區(qū)緯地路9號
Email: zhangxiangwen@cobioer.com
電話:4008750250
號碼:
手機:18066071954
地址:南京市棲霞區(qū)緯地路9號
Email: zhangxiangwen@cobioer.com
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CBP10267 | |
Format | Genomic DNA |
Description | EGFR G719S lies within the phosphate-binding “P loop" in the protein kinase domain of the Egfr protein (PMID: 17349580). G719S results in constitutive ligand-independent phosphorylation of Egfr, activation of Stat5, Erk1/2, and Akt, and is transforming in cell culture (PMID: 16204070, PMID: 24894453, PMID: 18573086, PMID: 29533785). |
Technical Data | |
DNA Change | c.2155G>A |
AA Change | p.G719S |
Mutation type | Substitution - Missense |
Zygosity | Heterozygous |
Allelic Frequency | 33.33% |
Transcript | ENST00000275493 |
Cosmic ID | COSM6252 |
Chr position(GRCh37) | chr7:55241707 |
Buffer | Tris-EDTA |
Product Information | |
Intended Use | Research Use Only |
Unit Size | 1ug |
Concentration | Download for COA |
Purofication | Download for COA |
DNA electrophoresis | Download for COA |
Sanger sequencing | |
Storage | 4℃ |
Expiry | 36 months from the date of manufacture |