名稱 | EGFR p.747_753LREATSP>S Reference Standard |
型號 | CBP10345 |
報價 | |
特點 | EGFR p.747_753LREATSP>S Reference Standard |
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聯(lián)系人:蔣經理
電話:4008750250
號碼:
手機:18066071954
地址:南京市棲霞區(qū)緯地路9號
Email: zhangxiangwen@cobioer.com
電話:4008750250
號碼:
手機:18066071954
地址:南京市棲霞區(qū)緯地路9號
Email: zhangxiangwen@cobioer.com
產品展示 / PRODUCTS
- 詳細內容
CBP10345 | |
Gene | EGFR |
Description | EGFR (HER1), epidermal growth factor receptor, is a tyrosine kinase receptor, which activates RAS/RAF/MEK and PI3K/AKT/mTOR pathways, leading to increased cell proliferation and growth (PMID: 24312144). EGFR activating mutations, amplification, and overexpression are found in a variety of tumor tumors, including non-small cell lung cancer (PMID: 26609494, PMID: 30284706) and colorectal cancer (PMID: 30243897), and the EGFRvIII variant is commonly found in glioblastoma (PMID: 30201736). |
Technical Data | |
DNA Change | c.2240_2257del18 TAAGAGAAGCAACATCTC>- |
AA Change | p.L747_P753LREATSP>S |
Mutation type | Deletion - In frame |
Zygosity | Heterozygous |
Allelic Frequency | 25.00% |
Transcript | ENST00000275493 |
Cosmic ID | COSM12370 |
Chr position(GRCh37) | chr7:55242470_55242487 |
Buffer | Tris-EDTA |
Product Information | |
Intended Use | Research Use Only |
Unit Size | 1ug |
Concentration | Download for COA |
Purofication | Download for COA |
DNA electrophoresis | Download for COA |
Sanger sequencing | |
Storage | 4℃ |
Expiry | 36 months from the date of manufacture |